Opening a small python file, with <10 buffers open, takes a long time. [Here's a gist of the profile](https://gist.github.com/vlad17/afb549b085f280ecbc503389ccf967ae) of trying to open this file (giving up with `C-g` after 2 minutes).

Deactivating ido-mode tells more or less the same story. See [this gist](https://gist.github.com/vlad17/dfb8eccc6f0a57b536a41e3c035deedc) for details.

Messages during the opening of the file:

	CPU profiler started
	Mark saved where search started [3 times]
	Making python-shell-interpreter local to  *Python Internal [792caf12c778150badeeede64c068cee]* while let-bound!
	Making python-shell-interpreter-args local to  *Python Internal [792caf12c778150badeeede64c068cee]* while let-bound!
	Waiting for process to die...done
	Quit

What's amazing is that after I quit the find-file with `C-g`, and re-open **the same** file with `C-x C-f` again, it loads, instantly. If, after this, I try to newly open another small python files, I have the exact same behavior - first time, emacs hangs, second time, emacs opens the file instantaneously.

None of the minor modes that are active seem threatening (I've removed all the cumbersome ones). Here are the minor modes that are activated in python mode (at least as captured when the file successfully opens the second time). 

Version

    GNU Emacs 24.5.1 (x86_64-pc-linux-gnu, GTK+ Version 3.18.9) of 2016-04-17 on lgw01-04, modified by Debian

Modes for buffer that's open while opening the file (same as the ones for the file that will be opened, they're all `*.py`):

	Enabled minor modes: Auto-Composition Auto-Compression Auto-Encryption
	Blink-Cursor Column-Number Electric-Indent File-Name-Shadow Font-Lock
	Global-Font-Lock Line-Number Menu-Bar Mouse-Wheel Shell-Dirtrack
	Tool-Bar Tooltip Transient-Mark

	(Information about these minor modes follows the major mode info.)

	Lisp Interaction mode defined in `lisp-mode.el':