It looks like the way to do this in LaTeX is to add this in the document body:
\mathversion{bold}
It doesn't look there is a way to do this out of the box with org, the document template is hard-coded in org-create-formula image. You can modify that function like this to achieve what you want.
You can put this in your init file.
(defun org-create-formula-image
(string tofile options buffer &optional processing-type)
"Create an image from LaTeX source using external processes.
The LaTeX STRING is saved to a temporary LaTeX file, then
converted to an image file by process PROCESSING-TYPE defined in
`org-preview-latex-process-alist'. A nil value defaults to
`org-preview-latex-default-process'.
The generated image file is eventually moved to TOFILE.
The OPTIONS argument controls the size, foreground color and
background color of the generated image.
When BUFFER non-nil, this function is used for LaTeX previewing.
Otherwise, it is used to deal with LaTeX snippets showed in
a HTML file."
(let* ((processing-type (or processing-type
org-preview-latex-default-process))
(processing-info
(cdr (assq processing-type org-preview-latex-process-alist)))
(programs (plist-get processing-info :programs))
(error-message (or (plist-get processing-info :message) ""))
(use-xcolor (plist-get processing-info :use-xcolor))
(image-input-type (plist-get processing-info :image-input-type))
(image-output-type (plist-get processing-info :image-output-type))
(post-clean (or (plist-get processing-info :post-clean)
'(".dvi" ".xdv" ".pdf" ".tex" ".aux" ".log"
".svg" ".png" ".jpg" ".jpeg" ".out")))
(latex-header
(or (plist-get processing-info :latex-header)
(org-latex-make-preamble
(org-export-get-environment (org-export-get-backend 'latex))
org-format-latex-header
'snippet)))
(latex-compiler (plist-get processing-info :latex-compiler))
(image-converter (plist-get processing-info :image-converter))
(tmpdir temporary-file-directory)
(texfilebase (make-temp-name
(expand-file-name "orgtex" tmpdir)))
(texfile (concat texfilebase ".tex"))
(image-size-adjust (or (plist-get processing-info :image-size-adjust)
'(1.0 . 1.0)))
(scale (* (if buffer (car image-size-adjust) (cdr image-size-adjust))
(or (plist-get options (if buffer :scale :html-scale)) 1.0)))
(dpi (* scale (if buffer (org--get-display-dpi) 140.0)))
(fg (or (plist-get options (if buffer :foreground :html-foreground))
"Black"))
(bg (or (plist-get options (if buffer :background :html-background))
"Transparent"))
(log-buf (get-buffer-create "*Org Preview LaTeX Output*"))
(resize-mini-windows nil)) ;Fix Emacs flicker when creating image.
(dolist (program programs)
(org-check-external-command program error-message))
(if use-xcolor
(progn (if (eq fg 'default)
(setq fg (org-latex-color :foreground))
(setq fg (org-latex-color-format fg)))
(if (eq bg 'default)
(setq bg (org-latex-color :background))
(setq bg (org-latex-color-format
(if (string= bg "Transparent") "white" bg))))
(with-temp-file texfile
(insert latex-header)
(insert "\n\\begin{document}\n"
"\\definecolor{fg}{rgb}{" fg "}\n"
"\\definecolor{bg}{rgb}{" bg "}\n"
"\n\\pagecolor{bg}\n"
"\n{\\color{fg}\n"
(or (plist-get options :latex-body-options) "")
string
"\n}\n"
"\n\\end{document}\n")))
(if (eq fg 'default)
(setq fg (org-dvipng-color :foreground))
(unless (string= fg "Transparent")
(setq fg (org-dvipng-color-format fg))))
(if (eq bg 'default)
(setq bg (org-dvipng-color :background))
(unless (string= bg "Transparent")
(setq bg (org-dvipng-color-format bg))))
(with-temp-file texfile
(insert latex-header)
(insert "\n\\begin{document}\n"
(or (plist-get options :latex-body-options) "")
string
"\n\\end{document}\n")))
(let* ((err-msg (format "Please adjust `%s' part of \
`org-preview-latex-process-alist'."
processing-type))
(image-input-file
(org-compile-file
texfile latex-compiler image-input-type err-msg log-buf))
(image-output-file
(org-compile-file
image-input-file image-converter image-output-type err-msg log-buf
`((?F . ,(shell-quote-argument fg))
(?B . ,(shell-quote-argument bg))
(?D . ,(shell-quote-argument (format "%s" dpi)))
(?S . ,(shell-quote-argument (format "%s" (/ dpi 140.0))))))))
(copy-file image-output-file tofile 'replace)
(dolist (e post-clean)
(when (file-exists-p (concat texfilebase e))
(delete-file (concat texfilebase e))))
image-output-file)))
Then, you can specify the latex-body-options in your init file with
(plist-put org-format-latex-options :latex-body-options "\\mathversion{bold}\n")
That may get you what you want. You may also want to use a different font, in which case you can either add it to org-latex-default-packages-alist, e.g.
(add-to-list 'org-latex-default-packages-alist '("" "fourier" t) t)
or you can add it to the latex header. Below I set the font to be fourier. I had to add it last, maybe because I have some other font package
(setq org-format-latex-header "\\documentclass{article}\n\\usepackage[usenames]{color}\n[PACKAGES]\n[DEFAULT-PACKAGES]\n\\usepackage{fourier}\n\\pagestyle{empty}
% do not remove\n% The settings below are copied from fullpage.sty\n\\setlength{\\textwidth}{\\paperwidth}\n\\addtolength{\\textwidth}{-3cm}\n\\setlength{\\oddsidemargin}{1.5cm}\n\\addtolength{\\oddsidemargin}{-2.54cm}\n\\setlength{\\evensidemargin}{\\oddsidemargin}\n\\setlength{\\textheight}{\\paperheight}\n\\addtolength{\\textheight}{-\\headheight}\n\\addtolength{\\textheight}{-\\headsep}\n\\addtolength{\\textheight}{-\\footskip}\n\\addtolength{\\textheight}{-3cm}\n\\setlength{\\topmargin}{1.5cm}\n\\addtolength{\\topmargin}{-2.54cm}")